16 days old

Senior Scientific Researcher, Biomarker Discovery

South San Francisco, CA 94080

The Biomarker Discovery OMNI department is seeking a motivated, interactive and flexible Senior Scientific Researcher to perform research related to biomarker discovery with a focus on intestinal mucosal and epithelial biology . The successful candidate will use in vitro and in vivo approaches to evaluate interactions between the immune system, gut microbiota and intestinal epithelium with the goal of identifying and monitoring changes in relevant biomarkers to disease. They will be expected to make intellectual as well as technical contributions and work effectively in a highly collaborative team setting.


Act as primary expert on epithelial organoids and/or engineered epithelial model systems for a team of researchers focused on inflammatory bowel disease. Manage external academic collaborations and drive internal technology efforts. Assist the team in evaluating epithelial cell function and response and identifying novel biomarkers and targets. Specific responsibilities will include: experimental design and planning, performing exploratory disease-oriented research utilizing samples & data from human disease cohorts, processing and analyzing clinical collaboration and trial samples, data analysis and presentation. Work may also be performed in pre-clinical models.


The successful applicant will have a PhD in immunology, developmental or cell biology, or related field, preferably with a background in mucosal immunology; 5+ years experience in academic or industry laboratory setting. Those familiar with techniques including intestinal epithelial organoid culture, epithelial barrier assays, and analysis of large clinical datasets will be given precedence. Good oral/written communication skills, problem-solving, flexibility, and the ability to integrate detailed analysis into a larger disease-oriented context will be expected.


Posted: 2020-05-20 Expires: 2020-06-19

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Senior Scientific Researcher, Biomarker Discovery

South San Francisco, CA 94080

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