1+ months


University of Washington
Seattle, WA 98104


Req #: 172318
Posting Date: 01/15/2020 
Closing Info: Open Until Filled 
Salary: Salary is commensurate with education and experience 
Shift: First Shift 
Notes: As a UW employee, you will enjoy generous benefits and work/life programs.  For detailed information on Benefits for this position, click here.

Please note that this position has been reposted. If you have already submitted your application, you need not submit it again, as it has already been received.  

As a UW employee, you have a unique opportunity to change lives on our campuses, in our state and around the world. UW employees offer their boundless energy, creative problem solving skills and dedication to build stronger minds and a healthier world.

UW faculty and staff also enjoy outstanding benefits, professional growth opportunities and unique resources in an environment noted for diversity, intellectual excitement, artistic pursuits and natural beauty. All of which has allowed the UW to be nationally recognized as a Great College to Work For for four consecutive years.

The Department of Biochemistry at the University of Washington has contributed to many phases of research. Initially recognized for incisive studies of the structure and function of proteins, and the mechanisms of enzyme action, the department branched out into a multitude of other areas. These included: developmental biology of flies, fish, frogs, and mice; molecular mechanisms of aging in yeast and mammals; vertebrate visual and immune responses; chromosome dynamics, cell division, DNA replication and repair; energy transduction during photosynthesis; protein secretion and membrane fusion; translational control and regulated protein degradation; protein structure determination by crystallography and NMR spectroscopy; and protein structure prediction and enzyme design. Our diversity of interests guarantees a rich intellectual and educational environment.

About the Institute for Protein Design:
The Institute for Protein Design (IPD) at the University of Washington in Seattle is creating a new world of synthetic proteins to address 21st-century challenges in medicine, energy, and technology. The IPD is a unique interdisciplinary environment where world-class researchers with expertise in computing and software, biochemistry, genome sciences, biological structure, pharmacology, immunology and other basic science disciplines, as well as clinical medicine, work together to both computationally design and experimentally characterize novel biomolecules. Current projects include the design of novel therapeutics for cancer, neurological diseases, and more, as well as new vaccines, nanomaterials, and enzymes.

The Institute of Protein Design within the Department of Biochemistry currently has an outstanding opportunity for a RESEARCH SCIENTIST 3.

The field of research that this postion Research Scientist / Engineer  3 (RES3) in Computer Science is engaged in software engineering of machine learning (ML) algorithms and Rosetta code (including GPU accelerated code) for molecular modeling, protein structure prediction and design.  For more detailed information about the Institute for Protein Design please see http://www.ipd.uw.edu/.

The RES3 is a key position within the Institute for Protein design, and will be directed at greatly improving the efficiency of Rosetta computational protein structure prediction and protein design.

The RES3 position will perform software engineering of specific machine learning (ML) algorithms and Rosetta code for use in GPU accelerated computing.  The research activities involves optimization of protein structure prediction with broad range utility for improving the Rosetta molecular modeling and design algorithms for the de novo computational protein design.

The primary responsibilities of the RES3 are:
  • Develop new machine learning algorithms for protein structure prediction and design.
  • Communicate with the Rosetta community to solicit and address feedback.
  • Collaborate with other research staff, postdoctoral fellows and graduate students on computational protein structure prediction and de novo protein design.
  • Participate in projects with uncertain outcomes requiring analysis from multiple perspectives. 
  • Trains others in how to use Rosetta software and protein design computing infrastructure.
  • Manages complex multi-task projects directed at improving computational protein structure prediction and design.
  • Uses expert knowledge and judgment to develop new methods and tools for protein structure prediction and design.

    In this role, ~90% of the effort will be dedicated to computational algorithm development for protein structure prediction and design.  The remaining ~10% of effort will be dedicated to preparing technical reports, publications in scientific journals and presenting project results to stakeholders.

    Minimum Requirements:
  • Doctoral Degree in Biochemistry, Computational Biology or Computer Science + 3 or more years of experience in related field.
  • Computational protein structure prediction and design with Rosetta, development of machine learning algorithms for protein structure prediction, various software languages and data base architectures, ability to work independently and in teams.

  • Deep learning algorithm development, Network development, Cross-platform (Linux/Windows/macOS) development, Experience in computational protein structure prediction, and design with Rosetta molecular design and modeling algorithms

    Application Process:
    The application process for UW positions may include completion of a variety of online assessments to obtain additional information that will be used in the evaluation process.  These assessments may include Work Authorization, Cover Letter and/or others.  Any assessments that you need to complete will appear on your screen as soon as you select Apply to this position. Once you begin an assessment, it must be completed at that time; if you do not complete the assessment you will be prompted to do so the next time you access your My Jobs page.  If you select to take it later, it will appear on your "My Jobs" page to take when you are ready. Please note that your application will not be reviewed, and you will not be considered for this position until all required assessments have been completed.
  • Committed to attracting and retaining a diverse staff, the University of Washington will honor your experiences, perspectives and unique identity. Together, our community strives to create and maintain working and learning environments that are inclusive, equitable and welcoming.

    The University of Washington is a leader in environmental stewardship & sustainability, and committed to becoming climate neutral.

    The University of Washington is an equal opportunity, affirmative action employer. To request disability accommodation in the application process, contact the Disability Services Office at 206-543-6450 / 206-543-6452 (tty) or dso@uw.edu.


    Posted: 2019-12-05 Expires: 2020-02-14

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    Seattle, WA 98104
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