1+ months

Oncology Data and Analytical Strategy Director

Site Name: USA - Pennsylvania - Upper Providence, USA - Massachusetts - Waltham
Posted Date: Jul 10 2020

Are you an experienced and innovative computational biology leader, interested in GSKs dynamic Oncology Synthetic Lethality department? Are you a candidate who is eager to join a Synthetic Lethality group that is rich in experimental and clinical data, while joining a leadership team to develop and implement analytical strategies in this field? If so, this

Oncology Data and Analytical Strategy Director role could be an ideal opportunity to explore.

As an Oncology Data and Analytical Strategy Director, you will work in a multidisciplinary, collaborative and scientifically driven environment, interacting with GSK scientists and external collaborators to advance our synthetic lethality pre-clinical pipeline as well as support new clinical indications for our approved PARP inhibitor, Zejula. This cutting-edge research addresses important drug discovery and development challenges and directly impacts GSKs R&D pipeline. Reflecting the importance of this position, the applicant will report directly to the head of the research unit and work in a matrix fashion with experimental and data scientists across GSK.

This role will provide YOU the opportunity to lead key activities to progress YOUR career. These responsibilities include some of the following:

  • Develop and implement computational strategies to translate existing synthetic lethality screening data into new target proposals
  • Support the selection of appropriate translational systems
  • Identify new investment opportunities & participate in due diligence exercises
  • Collaborate with GSKs experimental functional genomics, human genetics, biostatistics, and biomarker organizations on expanding PARP indications
  • Participate in drug discovery project teams with GSK scientists and external collaborators
  • Serve as part of the unit leadership team

Why you?

Basic Qualifications:

We are looking for professionals with these required skills to achieve our goals:

  • PhD or equivalent experience in computational biology, bioinformatics, computational sciences, machine learning or biomedical engineering/biological sciences
  • >5 years of pharmaceutical or biotech industry experience working on Oncology or Immuno-Oncology related projects

Preferred Qualifications:

If you have the following characteristics, it would be a plus:

  • Proficient in a programming language (such as R, Python or SQL)
  • Experience with databases such as TCGA, GTEx and CCLE
  • Experience of analysing and interpreting multi-omic data, especially RNA-Seq and single cell RNA-Seq, including data from patient samples
  • Data science skills to collect, integrate, mine and analyse complex biological data and translate them into testable hypotheses
  • Demonstrated skills working in teams to find creative ways to address scientific questions
  • Strong verbal and written communication skills and developing leadership skills for working with multidisciplinary teams and with international colleagues
  • Experience with genome-wide synthetic lethality screens & data
  • Understanding of cancer and immuno-oncology biology (pathways, mechanisms, cell types)
  • Application of pathway and network analysis methodology

Why GSK?

Our values and expectationsare at the heart of everything we do and form an important part of our culture. These include Patient focus, Transparency, Respect, Integrity along with Courage, Accountability, Development, and Teamwork. As GSK focuses on our values and expectations and a culture of innovation, performance, and trust, the successful candidate will demonstrate the following capabilities:

  • Operating at pace and agile decision-making using evidence and applying judgement to balance pace, rigour and risk.
  • Committed to delivering high quality results, overcoming challenges, focusing on what matters, execution.
  • Continuously looking for opportunities to learn, build skills and share learning.
  • Sustaining energy and well-being.
  • Building strong relationships and collaboration, honest and open conversations.
  • Budgeting and cost-consciousness.

*This is a job description to aide in the job posting, but does not include all job evaluation details


If you require an accommodation or other assistance to apply for a job at GSK, please contact the GSK Service Centre at 1-877-694-7547 (US Toll Free) or +1 801 567 5155 (outside US).

GSK is an Equal Opportunity Employer and, in the US, we adhere to Affirmative Action principles. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, national origin, religion, sex, pregnancy, marital status, sexual orientation, gender identity/expression, age, disability, genetic information, military service, covered/protected veteran status or any other federal, state or local protected class.

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Posted: 2020-07-08 Expires: 2020-09-09

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